Over 6 to 12 months, keto and low-carbohydrate diets lead to about as much weight loss as low-fat diets. Where keto came out ahead, the difference was small, and on average it raised LDL cholesterol. We found no study at all on the ‘boiled egg diet’. For the ‘units diet’ we found no study that looks at the units on their own. Programmes with units, weekly weigh-ins and a support group led to a few more kilos lost over a year. With every diet, the result depends mainly on whether you can keep to it.
Keto, the egg diet and the units diet each promise something different. Here we look at what the trials show, where there are any.
Keto and low-carbohydrate diets
Keto cuts carbohydrates sharply, usually to under 50 g a day. ‘Low-carbohydrate’ diets are milder. This is what the large comparisons with low-fat diets found:
| Study | What it found |
|---|---|
| DIETFITS, 609 adults, 12 months | low carbohydrate −6.0 kg, low fat −5.3 kg, no significant difference. Neither genes nor insulin secretion showed who would do better. |
| Analysis of 121 trials, 21,942 adults | at 6 months, compared with a usual diet, low carbohydrate −4.6 kg, low fat −4.4 kg. At 12 months the loss had become smaller with all diets. |
| Analysis of 13 keto trials, 12 months or more | keto lost 0.9 kg more. Triglycerides fell and HDL rose, but LDL rose too, by about 4.6 mg/dL. |
| Analysis of 11 trials, 1,369 people, 6 months or more | low carbohydrate lost 2.2 kg more, with LDL rising by about 6.2 mg/dL. The researchers say the benefit has to be weighed against the rise in LDL. |
It is fairly certain that keto gives at most a small extra weight loss and raises LDL on average. The analyses give averages. If you follow keto, it is worth having your cholesterol checked with your doctor.
Insulin. It is often said that keto makes you lose weight because it lowers insulin. In one study, 20 adults stayed in a clinic and ate as much as they wanted, two weeks on keto and two on a low-fat plant-based diet. On the second diet they ate 689 kcal a day less. The study was small and short, but it does not fit the idea that insulin is the key.
The first week's kilos. At the start of keto the scales drop fast, mainly because of water that leaves along with glycogen. See the article on the rate of weight loss.
Side effects. In a 24-week trial of 120 adults:
| Side effect | Keto | Low fat |
|---|---|---|
| Constipation | 68% | 35% |
| Headache | 60% | 40% |
| Bad breath | 38% | 8% |
| Muscle cramps | 35% | 7% |
| Weakness | 25% | 8% |
| Diarrhoea | 23% | 7% |
| Rash | 13% | 0% |
The trial was funded by the Robert C. Atkins Foundation, and only the keto group received supplements. So it is of low certainty. In this trial keto led to more weight loss.
What the guidelines say. The 2013 US guideline found no difference at 6 months between a low-carbohydrate and a low-fat diet. NICE (2025) says the deficit can be achieved in whatever way suits the person. It advises avoiding strict diets that are not balanced, because they do not work in the long term and may cause harm.
The MesogeaFit app has a ‘fewer carbohydrates’ option, with at least 40% of calories from carbohydrates, but no keto plan.
The boiled egg diet
Diets that go by this name have you eat mostly boiled eggs and a few other foods for one or two weeks. In October 2026 we searched two large databases of scientific studies and found no trial that tests it.
There are studies of eggs as part of an ordinary diet with fewer calories:
- 152 adults, 8 weeks: two eggs for breakfast, five days a week, together with a 1,000 kcal deficit, gave −2.6 kg against −1.6 kg with a bagel breakfast of the same calories. Without a deficit, the eggs made no difference. The study was funded by the US egg industry body.
- 110 adults, 6 months: eggs or cereal for breakfast, with fewer calories, gave 8.1 and 7.3 kg, with no difference. Funded by the Australian egg industry body.
- 128 adults with prediabetes or type 2 diabetes: with 12 or more eggs a week or with few eggs, weight loss was similar. No adverse changes in cardiometabolic health were seen over 12 months. We did not check who funded this study.
From these studies we conclude that eggs fit into a diet, but the result comes from the calories. A 50 g egg has about 70 kcal and 6 g of protein. A diet built on a single food is exactly the kind of unbalanced diet that NICE advises against. And the kilos that come off quickly in a week like this are largely water, which comes back.
The units diet
We found no official Greek source that defines the ‘units diet’. Systems that go by this name give each food a number of units or points, with a limit for each day. Some versions may count carbohydrate units instead of calories, but we have not confirmed this.
We found no trial comparing units with calorie counting. The trials that exist tested a whole commercial programme, Weight Watchers, known for its points system. In the largest trial, however, the programme is described as a diet with fewer calories, weekly weigh-ins, a discussion group and behavioural advice, with no mention of points.
| Trial | Result at 12 months | Funding |
|---|---|---|
| 772 adults in the UK, Germany and Australia | −5.1 kg with the programme, −2.3 with usual care | the company, through a grant to the UK's MRC |
| WRAP, 1,267 adults in England | −3.3 with brief advice, −4.8 with a 12-week programme, −6.8 with a 52-week programme | a public research body, with the company taking part |
| Lighten Up, 740 adults | 2.5 kg more than the comparison group | we did not check |
| Review of 45 studies | at least 2.6% more weight loss | no specific funding |
It is fairly certain that a programme with structure, weekly weigh-ins and support helps a little. Whether the units themselves add anything beyond calorie counting, we don't know. Units look like a simplified way of counting calories.
What they all have in common
In a one-year trial, 160 adults followed four well-known diets: Atkins, Zone, Weight Watchers and Ornish. They lost 2.1 to 3.3 kg, with no real difference between them. How much each person lost was related to how closely they followed their diet, not to which one they chose. An analysis of 48 trials with 7,286 adults concluded that the differences between diets are small, and that it is worth choosing the one you can keep to.
Who needs to be careful
- Keto and very low-carbohydrate diets: if you take SGLT2 inhibitors for diabetes, do not follow keto or a very low-carbohydrate diet. If you take insulin or sulphonylureas, do not try it without your doctor. In the clinic study, one healthy participant withdrew because of hypoglycaemia. Take care also in pregnancy and breastfeeding, with kidney disease, with high LDL or familial hypercholesterolaemia, with an eating disorder now or in the past, and under 18.
- Single-food diets: we do not recommend them for anyone, especially people who have or have had an eating disorder, in pregnancy, under 18 and with an egg allergy.
- Programmes with units: the two large trials reported no problems caused by the programme. The same exceptions apply as for any diet with a calorie deficit.
Sources
- Gardner CD et al. (2018). Effect of low-fat vs low-carbohydrate diet on 12-month weight loss in overweight adults and the association with genotype pattern or insulin secretion: the DIETFITS randomized clinical trial. JAMA 319(7):667-679. PubMed 29466592
- Ge L et al. (2020). Comparison of dietary macronutrient patterns of 14 popular named dietary programmes for weight and cardiovascular risk factor reduction in adults: systematic review and network meta-analysis of randomised trials. BMJ 369:m696. PubMed 32238384
- Johnston BC et al. (2014). Comparison of weight loss among named diet programs in overweight and obese adults: a meta-analysis. JAMA 312(9):923-933. PubMed 25182101
- Dansinger ML et al. (2005). Comparison of the Atkins, Ornish, Weight Watchers, and Zone diets for weight loss and heart disease risk reduction: a randomized trial. JAMA 293(1):43-53. PubMed 15632335
- Hall KD et al. (2021). Effect of a plant-based, low-fat diet versus an animal-based, ketogenic diet on ad libitum energy intake. Nature Medicine 27(2):344-353. PubMed 33479499
- Bueno NB et al. (2013). Very-low-carbohydrate ketogenic diet v. low-fat diet for long-term weight loss: a meta-analysis of randomised controlled trials. British Journal of Nutrition 110(7):1178-1187. PubMed 23651522
- Mansoor N et al. (2016). Effects of low-carbohydrate diets v. low-fat diets on body weight and cardiovascular risk factors: a meta-analysis of randomised controlled trials. British Journal of Nutrition 115(3):466-479. PubMed 26768850
- Yancy WS Jr et al. (2004). A low-carbohydrate, ketogenic diet versus a low-fat diet to treat obesity and hyperlipidemia: a randomized, controlled trial. Annals of Internal Medicine 140(10):769-777. PubMed 15148063
- Jensen MD et al. (2014). 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults. Circulation 129(25 Suppl 2):S102-S138. PubMed 24222017
- NICE (2025). Overweight and obesity management (NG246): Physical activity and diet. nice.org.uk
- Vander Wal JS et al. (2008). Egg breakfast enhances weight loss. International Journal of Obesity 32(10):1545-1551. PubMed 18679412
- Keogh JB, Clifton PM (2020). No difference in weight loss, glucose, lipids and vitamin D of eggs for breakfast compared with cereal for breakfast during energy restriction. International Journal of Environmental Research and Public Health 17(23):8827. PubMed 33261155
- Fuller NR et al. (2018). Effect of a high-egg diet on cardiometabolic risk factors in people with type 2 diabetes: the Diabetes and Egg (DIABEGG) Study, randomized weight-loss and follow-up phase. American Journal of Clinical Nutrition 107(6):921-931. PubMed 29741558
- Jebb SA et al. (2011). Primary care referral to a commercial provider for weight loss treatment versus standard care: a randomised controlled trial. Lancet 378(9801):1485-1492. PubMed 21906798
- Ahern AL et al. (2017). Extended and standard duration weight-loss programme referrals for adults in primary care (WRAP): a randomised controlled trial. Lancet 389(10085):2214-2225. PubMed 28478041
- Jolly K et al. (2011). Comparison of range of commercial or primary care led weight reduction programmes with minimal intervention control for weight loss in obesity: Lighten Up randomised controlled trial. BMJ 343:d6500. PubMed 22053315
- Gudzune KA et al. (2015). Efficacy of commercial weight-loss programs: an updated systematic review. Annals of Internal Medicine 162(7):501-512. PubMed 25844997
Last checked: October 2026. This article gives general information for adults and does not replace advice from a doctor or dietitian. If you find a mistake, write to us at info@mesogeafit.com.
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