At the same calories, 16/8 does not seem to lead to more weight loss than an ordinary diet. The 2026 Cochrane review found little or no difference, with low certainty. It helps people for whom it means eating less. We found no evidence that a late dinner ruins a diet. The calories of the whole day come first. Eating more earlier in the day may help a little, mainly because you feel less hungry. If you take medicines for diabetes, talk to your doctor first.
With 16/8 fasting you eat within an 8-hour window, for example from 12:00 to 20:00, and you don't eat for the other 16 hours. There are other forms of intermittent fasting, such as 5:2, with two days a week on very few calories, or alternate-day fasting. The question is whether they do anything more than a simple diet with fewer calories.
What the large reviews say
The Cochrane review of February 2026 brought together 22 randomised trials with 1,995 adults with overweight or obesity, followed for 6 months or more. Compared with standard dietary advice, intermittent fasting made little or no difference to weight loss, about 0.3 percentage points, with low certainty. For side effects the difference was also small, with very low certainty. The authors conclude that the choice is best made on the basis of what a person can keep up in practice.
A 2025 analysis in the BMJ, with 99 trials and 6,582 adults, found that all forms of fasting and daily calorie reduction lowered weight compared with changing nothing. Time-restricted eating, such as 16/8, was no better than daily calorie reduction. Only alternate-day fasting gave slightly more, about 1.3 kg, and not in the trials that lasted 24 weeks or more.
The UK's NICE looked at intermittent fasting in its 2025 guideline and made no recommendation for or against it. It said that for most outcomes fasting was not effective, and it called for more research.
Trials with an eating window
| Trial | What it compared | Result |
|---|---|---|
| 116 people, 12 weeks | 12:00 to 20:00 with no other instruction, or 3 meals | −0.94 and −0.68 kg, no significant difference |
| China, 139 people, 12 months | same calories, eaten within 08:00 to 16:00 or at any time | −8.0 and −6.3 kg, no significant difference |
| Chicago, 90 people, 12 months | 12:00 to 20:00 without counting, or calorie counting | about the same loss, both groups ate about 400 kcal less |
| 90 people, 14 weeks | 07:00 to 15:00 or a window of 12 hours or more, both with fewer calories | 2.3 kg more with the early window |
The trial in China gives the clearest answer. When calories were the same, the timing added almost nothing. This is fairly certain. In the Chicago trial, 16/8 worked as well as calorie counting, because participants ate less with both approaches. In the first trial, in the group that was measured precisely, 16/8 lowered fat-free mass in the arms and legs slightly more. This finding comes from a small group, but it is a reason to keep an eye on your protein.
Does eating in the evening make you put on weight?
If you eat dinner at 9 or 10 in the evening, this section is for you.
- A study in Spain of 420 people on a 20-week programme linked a late lunch, after 15:00, with less weight loss, 7.7 kg against 9.9 kg. Dinner time made no difference. Those who ate before 21:30 and those who ate after it lost about the same, 8.7 and 8.8 kg. The study did not assign meal times at random, so it does not show cause.
- Big breakfast or big dinner, at the same calories: in 30 adults, weight loss was the same. With the big breakfast they felt less hungry.
- In a small laboratory study of 16 people, the same food eaten 4 hours later increased hunger and slightly lowered the energy they used while awake, by about 59 kcal a day. The study lasted a few days and cannot tell us what happens to weight.
- Two reviews of trials found that when calories are moved earlier in the day, slightly more weight is lost, about 1.2 to 1.8 kg. The researchers behind one of them describe this as small, and in that review 22 of the 29 trials had a high risk of bias.
Overall, the evidence does not show that dinner at 9 or 10 ruins a diet. The day's calories come first. Eating more earlier may help a little, mainly because you feel less hungry. The finding is of low certainty.
Fruit in the evening
In October 2026 we searched for trials looking at fruit in the evening and body weight. We found none. The only related study we found is a large observational study of 133,468 adults in the US, followed for up to 24 years. Each extra daily serving of fruit was linked with about 0.24 kg less weight gain every 4 years. The time of day was not examined. So we know nothing certain about fruit in the evening, and we found no evidence that it makes you put on weight.
If you want to try 16/8
- Choose a window that suits your day. If you eat dinner at 9, a window from 13:00 to 21:00 is easier than an early one.
- Keep the same calories and the same protein as before. With two meals instead of three, the protein in each meal needs to be higher. See how much protein you need.
- If within a few weeks it makes you eat more in the evening or think about food all the time, stop and cut calories another way.
Orthodox Church fasting is a different thing. For that, see the article on fasting and protein.
Who should not fast on their own
- Diabetes treated with insulin or sulphonylureas: in a trial of people with type 2 diabetes, two days a week on 500 to 600 kcal doubled hypoglycaemic episodes, even though medicines were reduced. The trial was on 5:2, not 16/8, so this is indirect evidence. Talk to your doctor first. The same applies if you take SGLT2 inhibitors.
- Pregnancy: there are only small trials with a window of up to 10 hours and medical supervision. They showed no benefit for blood sugar, and in one of them the women were hungrier in the evening. Do not fast on your own.
- Breastfeeding: no fasting.
- An eating disorder now or in the past: in 2,762 teenagers and young adults in Canada, intermittent fasting was linked with eating disorder symptoms. The study does not show cause, but fasting is not a good idea in this situation.
- Under 18, low body weight, frail older people, or medicines that must be taken with food: talk to your doctor first.
Sources
- Garegnani LI et al. (2026). Intermittent fasting for adults with overweight or obesity. Cochrane Database of Systematic Reviews 2026(2):CD015610. PubMed 41692034
- Semnani-Azad Z et al. (2025). Intermittent fasting strategies and their effects on body weight and other cardiometabolic risk factors: systematic review and network meta-analysis of randomised clinical trials. BMJ 389:e082007. PubMed 40533200
- Lowe DA et al. (2020). Effects of time-restricted eating on weight loss and other metabolic parameters in women and men with overweight and obesity: the TREAT randomized clinical trial. JAMA Internal Medicine 180(11):1491-1499. PubMed 32986097
- Liu D et al. (2022). Calorie restriction with or without time-restricted eating in weight loss. New England Journal of Medicine 386(16):1495-1504. PubMed 35443107
- Lin S et al. (2023). Time-restricted eating without calorie counting for weight loss in a racially diverse population: a randomized controlled trial. Annals of Internal Medicine 176(7):885-895. PubMed 37364268
- Jamshed H et al. (2022). Effectiveness of early time-restricted eating for weight loss, fat loss, and cardiometabolic health in adults with obesity: a randomized clinical trial. JAMA Internal Medicine 182(9):953-962. PubMed 35939311
- Liu HY et al. (2024). Meal timing and anthropometric and metabolic outcomes: a systematic review and meta-analysis. JAMA Network Open 7(11):e2442163. PubMed 39485353
- Young IE et al. (2023). Distribution of energy intake across the day and weight loss: a systematic review and meta-analysis. Obesity Reviews 24(3):e13537. PubMed 36530130
- Ruddick-Collins LC et al. (2022). Timing of daily calorie loading affects appetite and hunger responses without changes in energy metabolism in healthy subjects with obesity. Cell Metabolism 34(10):1472-1485. PubMed 36087576
- Vujović N et al. (2022). Late isocaloric eating increases hunger, decreases energy expenditure, and modifies metabolic pathways in adults with overweight and obesity. Cell Metabolism 34(10):1486-1498. PubMed 36198293
- Garaulet M et al. (2013). Timing of food intake predicts weight loss effectiveness. International Journal of Obesity 37(4):604-611. PubMed 23357955
- Bertoia ML et al. (2015). Changes in intake of fruits and vegetables and weight change in United States men and women followed for up to 24 years: analysis from three prospective cohort studies. PLoS Medicine 12(9):e1001878. PubMed 26394033
- NICE (2025). Overweight and obesity management (NG246): Rationale and impact, intermittent fasting. nice.org.uk
- Corley BT et al. (2018). Intermittent fasting in Type 2 diabetes mellitus and the risk of hypoglycaemia: a randomized controlled trial. Diabetic Medicine 35(5):588-594. PubMed 29405359
- Skarstad HMS et al. (2024). A randomized feasibility trial of time-restricted eating during pregnancy in people with increased risk of gestational diabetes. Scientific Reports 14:22476. PubMed 39341847
- Sujan MJ et al. (2025). Time restricted eating and exercise training before and during pregnancy for people with increased risk of gestational diabetes: single centre randomised controlled trial (BEFORE THE BEGINNING). BMJ 390:e083398. PubMed 40925657
- Ganson KT et al. (2022). Intermittent fasting: describing engagement and associations with eating disorder behaviors and psychopathology among Canadian adolescents and young adults. Eating Behaviors 47:101681. PubMed 36368052
Last checked: October 2026. This article gives general information for adults and does not replace advice from a doctor or dietitian. If you find a mistake, write to us at info@mesogeafit.com.
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